Mayo clinic researchers test novel injection of gene therapy vectors into the kidney

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Doctor with stethoscope
Valley News - Health
NEW ROCHELLE, N.Y. – Before gene therapy can be used to treat renal diseases, delivery of therapeutic genes to the kidney must become much more efficient. A novel approach in which three different gene delivery vectors were injected intravenously and directly into the kidneys of mice was reported in an article published in Human Gene Therapy, a peer-reviewed journal from publisher Mary Ann Liebert Inc. Jeffrey Rubin, Tien Nguyen, Kari Allen, Katayoun Ayasoufi and Michael Barry of the Mayo Clinic wrote the article entitled “Comparison of Gene Delivery to the Kidney by Adenovirus, Adeno-Associated Virus and Lentiviral Vectors after Intravenous and Direct Kidney Injections.” As the kidney filters out large compounds from the bloodstream, the researchers chose to study the ability to
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