Drug can curb dementia’s delusions, researchers find

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Nuplazid is a drug that was tested for treating psychosis related to dementia. The drug could become the first treatment specifically for dementia-related psychosis and the first new medicine for Alzheimer's in nearly two decades. Courtesy photo/Acadia Pharmaceuticals Inc.
A drug that curbs delusions in Parkinson’s disease patients did the same for people with Alzheimer’s disease and other forms of dementia in a study that was stopped early because the benefit seemed clear. If regulators agree, the drug could become the first treatment specifically for dementia-related psychosis and the first new medicine for Alzheimer’s disease in nearly two decades. It targets some of the most troubling symptoms that patients and caregivers face – hallucinations that often lead to anxiety, aggression, and physical and verbal abuse. Results were disclosed Wednesday, Dec. 4, at a conference in San Diego. “This would be a very important advance,” one independent expert, Dr. Howard Fillit, chief science officer of the Alzheimer’s Drug Discovery Foundatio
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